Changes in hormone levels can affect much more than how you feel on a particular day. Fatigue, poor sleep, brain fog, changes in mood, weight gain, hot flashes, reduced strength, and a decline in sexual wellness can gradually interfere with work, relationships, exercise, and everyday life.
At Lakota Wellness, we provide hormone replacement therapy in Ocoee, FL for women and men using the EvexiPEL® Protocol. This personalized approach combines hormone testing, an individualized clinical evaluation, bioidentical hormone pellets, and ongoing monitoring. Our goal is to understand what may be contributing to your symptoms and help you feel more energetic, focused, balanced, and like yourself again.
What Is the EvexiPEL® Protocol?

The EvexiPEL® Protocol is a personalized method of bioidentical hormone replacement therapy for women and men. It primarily uses estradiol and testosterone pellets that are placed beneath the skin and gradually release hormones into the body.
At Lakota Wellness, EvexiPEL® is our hormone therapy protocol. We do not select a standard dose based on symptoms alone. We consider your health history, symptoms, medications, lifestyle, wellness goals, and laboratory findings before determining whether you may be a candidate. Your dosage is then calculated for your individual hormone needs and health profile.
Bioidentical hormones are designed to closely match hormones naturally produced by the body. For women, treatment may address changes associated with perimenopause, menopause, or hormonal decline. For men, it may address symptoms associated with declining testosterone and other hormone changes.
How Does EvexiPEL® Hormone Pellet Therapy Work?
EvexiPEL® pellets are small—often compared in size to a grain of rice. During a brief in-office procedure, the pellets are placed beneath the skin through a small incision, commonly near the upper buttock or hip. Once placed, they gradually dissolve and release hormones over several months.
This delivery method does not require a daily pill, cream, or injection. Because the pellets provide ongoing hormone delivery, treatment is designed to support steadier levels between visits. Placement is performed by a provider trained in the EvexiPEL® technique, and patients receive clear instructions regarding activity and care of the placement area afterward.
Hormone Therapy Patient Tools
Use these resources from Lakota Wellness to learn more about hormone health and prepare for a personalized conversation with our team.

Scan to Take the Hormone Health Self-Assessment
Start the Hormone Health Self-Assessment
Enroll in Patient Education
Potential Benefits of Hormone Replacement Therapy
Hormones influence energy production, sleep, mood, cognition, metabolism, muscle maintenance, and sexual wellness. When an evaluation identifies hormone levels that may be contributing to symptoms, personalized treatment may help support:
Potential benefits may include more consistent energy and stamina, improved sleep and mental clarity, a more stable mood, support for libido and sexual wellness, healthier muscle maintenance and exercise recovery, and relief from certain hot flashes, night sweats, and related concerns.
Every patient responds differently. We evaluate progress based on how you feel, your laboratory results, and the health goals established during your evaluation—not simply whether one number falls within a reference range.
Signs You May Have a Hormone Imbalance

Women and men often experience hormone changes differently. Signs that may indicate it is time to evaluate your hormone levels include:
- Persistent fatigue, low energy, or reduced stamina
- Difficulty sleeping or waking without feeling rested
- Brain fog, poor concentration, or memory concerns
- Mood changes, irritability, anxiety, or low motivation
- Hot flashes, night sweats, or other menopause-related symptoms
- Low libido, vaginal dryness, or changes in sexual function
- Loss of strength, reduced muscle tone, or slower exercise recovery
- Weight gain or changes in body composition
These symptoms are not always caused by a hormone imbalance. That is why we do not recommend treatment based on symptoms alone. An EvexiPEL® evaluation helps us review the full picture and determine whether hormone testing and pellet therapy are appropriate for you.
Patients throughout Ocoee, Winter Garden, Windermere, Clermont, and nearby communities can also explore our sexual health services and personalized weight-loss care when those concerns overlap with hormone health.
What to Expect From Your Hormone Therapy Evaluation and Treatment
Your first visit gives us the opportunity to understand what has changed, how long symptoms have been present, and how they affect your quality of life. From there, the EvexiPEL® process generally includes:
- Personal evaluation: We discuss your symptoms, medical history, medications, lifestyle, and goals.
- Laboratory testing: Appropriate testing helps us evaluate hormone levels and related health markers.
- Personalized recommendation: If you are a candidate, we explain your EvexiPEL® dosage and what the placement process involves.
- Pellet placement: The pellets are placed during a brief office visit, followed by straightforward aftercare instructions.
- Monitoring: Follow-up visits and laboratory testing help us evaluate your response and plan future treatment.
We want you to understand each step before treatment begins. Our Ocoee team takes time to answer questions and explains what to expect before, during, and after pellet placement.
Schedule a Hormone Therapy Evaluation in Ocoee, FL
If fatigue, poor sleep, brain fog, mood changes, low libido, hot flashes, reduced strength, or other possible hormone-related symptoms are affecting your daily life, an individualized evaluation is the right place to begin.
Contact Lakota Wellness today at (407) 877-8707 or request an appointment online to schedule your EvexiPEL® evaluation in Ocoee, FL.
